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Chicken Zucchini Casserole with Stuffing

This Chicken Zucchini Casserole with Stuffing features rotisserie chicken, two kinds of squash, a creamy sauce, and a crunchy cheesy stuffing topping. It’s a delicious way to use up your garden produce and is a great option for Thanksgiving leftovers!

Zucchini casserole with chicken on green plate with gold fork and kitchen towel nearby.

I love zucchini and I love growing it in my garden every year!

My family, on the other hand, does not love zucchini.

However, everyone loves this chicken zucchini casserole, even my husband, who normally shies away from recipes with zucchini in them.

This recipe works because it’s:

  • So flavorful. The stuffing mix gives this recipe all of its delicious flavor. You’ll get a tasty recipe without having to use a ton of spices.
  • A great recipe for excess zucchini. Those of use who grow zucchini know how hard it can be to use it all up before it goes bad. This is a yummy option.
  • Easy to throw together! You won’t need to do any cooking for this casserole. Just mix everything together and dinner is underway.

This recipe was adapted from Six Sisters Stuff.

Step-by-Step Instructions

Chicken zucchini casserole ingredients in bowls including stuffing mix, melted butter, and parmesan cheese.

Preheat your oven to 350 degrees.

Combine 6 ounces of savory herb stuffing mix, 1/2 cup of melted butter, and 1 cup of shredded Parmesan cheese in a large mixing bowl. Remove 1 cup of the stuffing to use for the topping and set aside.

Stuffing mixture with parmesan cheese in small metal bowl on white table.

Add 4 cups of rotisserie chicken (or leftover turkey), 1 diced medium zucchini, 1 diced medium yellow squash, 10.5 ounces of cream of chicken soup, 1/2 cup of sour cream, and 1 teaspoon of onion powder to the large mixing bowl. Mix well.

Diced zucchini and rotisserie chicken in metal mixing bowl with wooden spoon.

Spread the chicken and zucchini mixture into a lightly greased 9×13 baking dish.

Creamy chicken and zucchini mixture in white baking dish on white table.

Top with the reserved stuffing mixture and bake uncovered for 40-50 minutes or until the squash is tender and the top is golden brown.

Unbaked chicken zucchini casserole in white baking dish on white table.

Recipe Tips and Substitutions

White baking dish with zucchini chicken casserole on table with green plate and gold fork nearby.

This is a great recipe to use with Thanksgiving leftovers! Just substitute the chicken for turkey. You could even use green beans instead of the zucchini.

This recipe is delicious as written, but you could try these additions for a change in flavor:

  • Dried cranberries
  • Chopped broccoli
  • Shredded carrots
  • Diced onion
  • Sliced mushrooms
  • Use canned chicken instead of rotisserie chicken
  • Use cream of mushroom soup instead of cream of chicken soup
  • Chopped celery
  • Chopped potatoes
  • Cooked rice

If you’re out of certain ingredients, try these substitutes:

The best way to reheat this casserole is in the oven if you have several portions, or in a skillet with a little bit of water if you’re only heating up one portion.

More Like This

Wooden spoon in chicken zucchini casserole with stuffing and parmesan cheese.

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FAQs

Chicken with Stove Top and zucchini casserole in white baking dish with wooden spoon and plate of casserole nearby.
What can I use instead of sour cream in this recipe?


Many people with substitute Greek yogurt for the sour cream. Or you can try one of these sour cream substitutes.

Can this casserole be frozen?


Yes, this casserole freezes well. Make the recipe in a disposable pan without baking it and cover with plastic wrap and foil to seal well. When you’re ready to eat it, you can leave it in your refrigerator to defrost or you can bake it frozen.

You’ll need to add more cooking time since the casserole is frozen. It will need to cook for 80-100 minutes at 350 degrees.

Do I need to cook the squash before adding it to the casserole?


No, the squash should be added raw so that it cooks in the oven.

Is there a way to make this in the slow cooker?


This casserole is not made for a slow cooker. The stuffing mix will get soggy and mushy and will not turn out well. Cooking it in the oven crisps the stuffing nicely so you get a variety of textures in each bite.

I hope your family loves this chicken zucchini casserole! If you make it, be sure to take a picture and tag me on Instagram with @ashcroftfamilytable and use the hashtag #ashcroftfamilytable!

 

And if you’d like to get a 4-week meal plan featuring my recipes, just enter your email in the form above and you’ll get it straight to your inbox!

Zucchini casserole with chicken on green plate with gold fork and kitchen towel nearby.

Chicken Zucchini Casserole with Stuffing

The Ashcroft Family Table
This Chicken Zucchini Casserole with Stuffing features rotisserie chicken, two kinds of squash, a creamy sauce, and a crunchy cheesy stuffing topping. It's a delicious way to use up your garden produce!
4.67 from 3 votes
Prep Time 10 minutes
Cook Time 40 minutes
Total Time 50 minutes
Course Dinner
Cuisine American
Servings 8
Calories 407 kcal

Ingredients
 
 

  • 6 ounces savory herb stuffing mix, dry
  • ½ cup melted butter, 1 stick
  • 1 cup shredded Parmesan cheese
  • 4 cups rotisserie chicken
  • 1 medium zucchini, diced
  • 1 medium yellow squash, diced
  • 10.5 ounces canned cream of chicken soup
  • ½ cup sour cream
  • 1 teaspoon onion powder

Instructions
 

  • Preheat oven to 350 degrees.
  • Combine stuffing mix, melted butter, and Parmesan cheese in a large mixing bowl. Remove 1 cup of the stuffing to use for the topping and set aside.
  • Add rotisserie chicken, zucchini, yellow squash, cream of chicken soup, sour cream, and onion powder to the stuffing in the large mixing bowl. Mix well.
  • Spread the chicken and zucchini mixture into a lightly greased 9×13 baking dish.
  • Top with the reserved stuffing mixture and bake uncovered for 40-50 minutes or until the squash is tender and the top is golden brown.

Video

Nutrition

Serving: 1serving | Calories: 407kcal | Carbohydrates: 22g | Protein: 29g | Fat: 23g | Saturated Fat: 12g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 7g | Trans Fat: 0.5g | Cholesterol: 113mg | Sodium: 1097mg | Potassium: 441mg | Fiber: 1g | Sugar: 4g | Vitamin A: 720IU | Vitamin C: 9mg | Calcium: 210mg | Iron: 2mg
Keyword chicken with stove top casserole, chicken zucchini casserole, zucchini casserole with chicken
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