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Chicken and Broccoli Casserole with Mayo

This Chicken and Broccoli Casserole with Mayo is so simple to make, you probably have the ingredients in your pantry and fridge right now! It tastes like a Sunday dinner, but it’s easy enough to prepare any night of the week.

Chicken and broccoli casserole with mayo in a casserole dish.

Chicken and broccoli casserole with mayo is one of my husband’s favorite dinners.

His mom made it often growing up, so I decided to continue the family tradition. It’s such an easy dish to make and pretty cheap too. I often have all of the ingredients on hand already.

However, it always felt like it was missing something so I decided to start serving it over white rice.

The creamy sauce soaks into the rice and it pulls the dish together perfectly if I do say so myself!

FAQs

Spoon full of chicken broccoli casserole.
Can you cook a casserole with raw chicken?

Generally, no.

Usually, any grains or vegetables in a dish would be overcooked and mushy by the time the meat is done, so most casseroles use pre-cooked proteins.

However, if your casserole ingredient list includes raw grains or hearty vegetables like carrots or potatoes, it’s possible to use uncooked meat.

Just be sure to cut the protein into smaller pieces so it cooks quickly and that you check for complete doneness before digging in!

Do I need to cover a casserole in the oven?

As a rule of thumb, if a recipe has uncooked grains (rice, pasta, couscous, etc.), it should always be covered, and casserole dishes with pre-cooked ingredients can be left uncovered.

However, if a recipe is topped with cheese, you may need to cover the dish to ensure the cheese melts completely, which depends on the type of cheese, the cook time and temperature.

You can remove the cover for the final minutes of cooking for a crispier, caramelized finish.

What goes well with chicken casserole?

I always serve this recipe with cooked rice, fruit, and rolls.

You could also try these delicious, cheesy drop biscuits that only take 20 minutes to make!

How to make Chicken and Broccoli Casserole with Mayo – Step by Step

Chicken broccoli casserole ingredients on a table.

COOK 3 chicken breasts as desired (pan fried, shredded, or boiled).

Shredded chicken in metal pot.

COOK (1) 12 oz. bag frozen broccoli in the microwave in the package (if it’s steamable) or in a microwave-safe dish with a little water in the bottom until warm.

LAYER the chicken and broccoli in a 9 x 13 casserole dish.

Cooked broccoli and chicken in a casserole dish.

In a medium bowl, MIX together 1 can cream of chicken soup, ½ cup mayonnaise, 1 tablespoon lemon juice, ½ cup milk, ¼ teaspoon pepper and ½ teaspoon paprika and POUR on top of the chicken and broccoli.

Chicken broccoli casserole sauce.

SPRINKLE with grated Parmesan cheese and BAKE at 350 degrees for 25 minutes until heated through.

Parmesan cheese on chicken broccoli casserole.

SERVE over cooked rice.

Recipe Tips and Substitutions

Chicken and broccoli bake over rice.

You can prepare the chicken a number of ways. I like to cube it and cook it in a frying pan. You could also boil the chicken breasts and cut them. Or you could prepare the chicken in your Instant Pot and shred it.

If you don’t like frozen broccoli, you could substitute fresh broccoli. The frozen broccoli is definitely more convenient, though.

If you want an extra creamy sauce, add in another can of cream of chicken soup. My sister-in-law made it this way recently and it was super tasty!

You can substitute sour cream for the mayonnaise for a tangy sauce.

Try adding breadcrumbs with the Parmesan cheese for an added crunch!

More Like This

Chicken broccoli casserole recipe in a casserole dish.

Looking for more chicken recipes? You’ll love these!

I hope your family enjoys this chicken and broccoli casserole with mayo as much as mine! If you make it, be sure to take a picture and tag me on Instagram with @ashcroftfamilytable and use the hashtag #ashcroftfamilytable!

 

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Chicken broccoli casserole recipe in a casserole dish.

Chicken and Broccoli Casserole with Mayo

The Ashcroft Family Table
Chicken and Broccoli Casserole with mayo is a creamy casserole made with simple pantry ingredients. Served over rice, you can have that Sunday dinner taste any night of the week!
4.34 from 3 votes
Prep Time 15 mins
Cook Time 25 mins
Total Time 40 mins
Course Dinner
Cuisine American
Servings 6 servings
Calories 335 kcal

Ingredients
  

  • 3 chicken breasts, thawed and trimmed of fat
  • 1 12 ounce bag frozen broccoli
  • 1 10.5 ounce can cream of chicken soup
  • ½ cup mayonnaise
  • 1 tablespoon lemon juice
  • ½ cup milk
  • ¼ teaspoon pepper
  • ½ teaspoon paprika
  • Grated parmesan cheese
  • Cooked rice

Instructions
 

  • Preheat oven to 350 degrees.
  • Cook chicken as desired (pan-fried, shredded, or boiled). Cook broccoli in the microwave in the package (if it’s steamable) or in a microwave-safe dish with a little water in the bottom until warm.
  • Layer in a 9 x 13 casserole dish.
  • Mix remaining ingredients, except cheese, and pour on top of the chicken and broccoli.
  • Sprinkle with cheese.
  • Bake at 350 degrees for 25 minutes until heated through. Serve over cooked rice.

Notes

For a creamier sauce, use 2 cans of cream of chicken soup.

Nutrition

Serving: 1gCalories: 335kcalCarbohydrates: 16gProtein: 23gFat: 20gSaturated Fat: 4gPolyunsaturated Fat: 14gCholesterol: 65mgSodium: 551mgFiber: 2gSugar: 1g
Keyword chicken and broccoli bake, chicken and broccoli casserole with mayo, chicken broccoli casserole, chicken broccoli casserole recipe
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